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The FDA Just Rewrote the Rules on Testosterone Therapy. Here's What It Means for You.
If you've been on the fence about testosterone replacement therapy (TRT) — or you've heard secondhand warnings about heart attacks and prostate cancer that made you hesitate — the conversation just changed. On June 18, 2026, the U.S. Department of Health and Human Services and the FDA announced a major request to update the prescribing labels on every testosterone replacement product on the market. This isn't a minor footnote. It's the most significant shift in TRT regulation
David Cesarino, PA-C, MPAS
Jun 225 min read


The Silent Threat: What Low Testosterone Is Really Doing to Your Body
Most men chalk it up to getting older — the fatigue, the brain fog, the stubborn belly fat that won't budge no matter what they do. But what if aging isn't the enemy? What if the real culprit is something measurable, treatable, and far more dangerous than most men realize? Low testosterone — clinically known as hypogonadism — affects an estimated 4 to 5 million American men, yet the vast majority go undiagnosed. That's not just a statistic. It's millions of men operating belo
David Cesarino, PA-C, MPAS
Jun 55 min read


Explain MOTS-c to me like I'm 5.
Hey, in Layman’s Terms: What Does MOTS-c Do? Imagine your body’s cells have tiny power plants inside them called mitochondria. These little engines turn the food you eat into energy that keeps everything running — from your muscles moving to your brain thinking. But sometimes these power plants get sluggish, especially as we age, sit too much, or eat poorly. That’s where MOTS-c comes in. So… What Exactly Is MOTS-c? MOTS-c (short for Mitochondrial Open Reading Frame of the 12S
David Cesarino, PA-C, MPAS
May 273 min read
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